Being unvaccinated and contact with measles cases as the risk factors of measles outbreak, North Sumatera, Indonesia

a:4:{i:0;s:318:"Background: Measles is a highly contagious and a vaccine-preventable disease. On 14 August 2015, a measles outbreak was reported in Langkat District, North Sumatra province of Indonesia. To investigate the risk factors of the outbreak and to recommend control measures, an epidemiological investigation was undertaken.";i:1;s:457:"Method: A 1:1 matched case-control study was conducted. All suspect and confirmed cases were recruited and included. Controls were healthy neighbors of cases, matched for age and gender. House-to-house search for cases was carried out. Structural interviews were conducted to solicit demographic data, clinical data, as well as the risk factors. A two-step logistic regression was employed to assess the potential risk factors associated with the infection.";i:2;s:689:"Results: During 20 July to 25 September 2015, a total of 28 measles cases were identified with no death. All tested blood samples were positive for measles-specific IgM antibodies confirming the outbreak. All cases presented with fever and rash; cough (80%), coryza (65%), and conjunctivitis (25%). The attack rate (AR) was 14.1% (age ranged between 1 and 14 years old), the highest AR (50.0%) occurred among those aged 1-4 years. In multivariate model, those who have not received measless vaccication and those who had contact with a measles case had higher odds of having infection, with adjusted odds ratio (aOR): 2.31 (95%CI: 1.22-4.27) and aOR: 1.15 (95%CI: 1.12-3.70), respectively.";i:3;s:317:"Conclusions: Being unvaccinated and having a contact history increased the risk of measles are two risk factors of measles infection. A mass measles immunization to the school children was undertaken and a strict measles surveillance and notification system were recommended to control the transmission in the future.";}