Interactions of polysulfanes with components of red blood cells

Publication Name : MEDCHEMCOMM

DOI : 10.1039/c0md00203h

Date : MAR 2011


Traditionally, the activity of most polysulfanes has been associated with the redox behaviour of the sulfur-sulfur bond. Here we show that polysulfanes, such as diallyltri- and tetrasulfide, also interact with cellular membranes and certain metalloproteins. Together, multiple interactions with various biological targets may explain best the biological activity of such compounds.

Type
Journal
ISSN
2040-2503
EISSN
Page
196 - 200